Durham, North Carolina
Element Clinical Research, LLC is a physician-led clinical research organization specializing in metabolic, thyroid, and endocrine disorders — bridging academic rigor with real-world patient care.
About Us
Element Clinical Research, LLC is a Durham, NC–based clinical research organization founded by a board-certified endocrinologist with deep expertise in metabolic disease, diabetes technology, and hormone disorders.
We operate at the intersection of clinical practice and investigational medicine — offering sponsor companies, academic partners, and healthcare networks a credentialed, efficient research infrastructure grounded in real endocrine specialty care.
Our work is guided by a commitment to scientific rigor, ethical conduct, and meaningful outcomes for patients with complex metabolic conditions.
GCP-trained physician leadership with IRB experience and subspecialty endocrinology expertise across diabetes, thyroid, bone, and obesity medicine.
Structured for pharma and device company collaboration — from feasibility assessment and site qualification to full trial execution.
Lean, physician-owned infrastructure built for quality, speed, and regulatory compliance — without the overhead of large academic centers.
What We Do
From early-phase feasibility through late-stage observational studies, Element Clinical Research offers a full suite of investigational and advisory services.
Serve as a qualified investigational site for Phase II–IV endocrine and metabolic trials. GCP-compliant processes, IRB liaison, and experienced physician PI.
Pharma & DeviceRapid feasibility assessments, patient population analysis, and site readiness evaluation for sponsor companies considering endocrine indication trials.
SponsorsPhysician advisory services for medtech, digital health, and pharmaceutical companies developing products in diabetes, thyroid, obesity, and hormone health.
IndustryDeep expertise in CGM systems, insulin pumps, and closed-loop technology. Advisory, clinical review, and real-world validation support.
MedTechClinical protocol review and endocrinology-specific input for CROs, sponsors, and academic investigators designing metabolic or endocrine studies.
CROs & AcademiaDirect patient care in diabetes, thyroid disease, osteoporosis, obesity, adrenal disorders, PCOS, and metabolic syndrome through Element Endocrinology.
PatientsLeadership
Nicholas Fiacco, MD
Principal Investigator & Founder
Board-certified endocrinologist, physician-owner of Element Endocrinology and Diabetes, PLLC, and founder of Element Clinical Research, LLC. Based in Durham, NC.
Clinical Specialties
Research & Academic
Prior Positions
Get in Touch
Whether you're a sponsor seeking an endocrine trial site, a CRO evaluating feasibility, or a medtech company seeking physician advisory — we'd like to hear from you.
Location
Durham, North Carolina
Affiliated Practice
Element Endocrinology and Diabetes, PLLC